应用
3-Bromopyridine undergoes lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with strong acids.

基本信息

MDL
MFCD00006373

EINECS
210-952-0

分子式
C₅H₄BrN

分子量
158.00

熔点
-27°

沸点
172-174°

闪点
72°(181°F)

密度
1.617

折射率
1.5700

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Soluble in water (31 g/L at 20°C).

Beilstein
105880

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H302-H311-H332-H315-H319-H335
Combustible liquid.Harmful if swallowed.Toxic in contact with skin.Harmful if inhaled.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P280h-P305+P351+P338-P309-P310a
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:

安全信息

危险等级
6.1

包装组
II

危险类别
20/21/22-36/37/38
Harmful by inhalation, in contact with skin and if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

TSCA
是