应用
Bromomethyl methyl ether is used as reagent for protection of OH groups as their methoxymethyl (MOM) ethers. It is used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone.

备注
Moisture Sensitive. Store at 4?°C. Do not store together with acids. Store away from water and strong bases. Incompatible with acids, bases, moisture, heat and oxidizing agents.

基本信息

MDL
MFCD00000171

分子式
BrCH₂OCH₃

分子量
124.97

沸点
86-87°

闪点
26°(78°F)

密度
1.531

折射率
1.4520-1.4600

灵敏度
Keep Cold. Moisture Sensitive. Store under Nitrogen.

形态
Liquid

溶解性
Sparingly soluble in water.

Beilstein
1730853

GHS危害和防范说明

GHS符号

Hazard Statements
H226-H302-H312-H332-H315-H319-H351-H335
Flammable liquid and vapour.Harmful if swallowed.Harmful in contact with skin.Harmful if inhaled.Causes skin irritation.Causes serious eye irritation.Suspected of causing cancer.May cause respiratory irritation.

Precautionary Statements
P210-P201-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Obtain special instructions before use.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
III

危险类别
10-20/21/22-36/37/38-40
Flammable.Harmful by inhalation, in contact with skin and if swallowed.Irritating to eyes, respiratory system and skin.Limited evidence of a carcinogenic effect.

安全等级
9-23-26-36/37-60
Keep container in a well-ventilated place.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA
是